Overdosage of cholestyramine resin has been documented in the affected person using one hundred fifty% of the utmost encouraged day by day dosage to get a duration of several weeks. No sick results were documented.
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Reduction of serum or red cell folate is reported in excess of long term administration of cholestyramine resin. Supplementation with folic acid needs to be regarded as in these cases.
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The utmost proposed day by day dose is six packets or scoopfuls of Prevalite® (cholestyramine for oral suspension, USP) powder (24 grams of anhydrous cholestyramine resin). The advised time of administration is at mealtime but can be modified to prevent interference with absorption of other medicines. Although the suggested dosing program is twice every day, Prevalite® (cholestyramine for oral suspension, USP) powder may very well be administered in 1 to 6 doses every day.
Cholesterol might be the sole precursor of bile acids. During ordinary digestion, bile acids are secreted to the intestines.
Other activities (not automatically drug similar) documented in clients taking cholestyramine resin consist of:
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Sipping or holding the resin suspension in the mouth for extended intervals may possibly result in changes while in the surface area of your tooth leading to discoloration, erosion of enamel or decay; fantastic oral hygiene should be maintained.
Cholestyramine resin may well create or worsen pre-existing constipation. The dosage needs to be increased gradually in people to minimize the potential risk of building fecal impaction. In people with pre-existing constipation, the starting off dose need to be 1 packet or one scoop at the time everyday for five to 7 times, raising to two times everyday with monitoring of constipation and of serum lipoproteins, not less than two times, four to 6 months apart. Increased fluid intake and fiber consumption must be encouraged to alleviate constipation in addition to a stool softener may perhaps from time to time be indicated.